Laird Advances DNA Replication Process with New PCR Cycler

August 17, 2015, 8:00 pm


Unique application of thermoelectric technology enables quick, accurate replication of DNA due to industry leading temperature control and monitoring features

 

Global technology leader Laird (LRD: London) is lowering the barriers-to-entry and increasing service differentiation for both manufacturers and solution providers of medical equipment with the release of a new PCR (Polymerase Chain Reaction) Cycler Evaluation Kit .

 Lairdís new Evaluation Kit enables faster and more reliable results for DNA replication processes. This allows medical equipment manufacturers and solutions providers to offer their customers more reliable and accurate results in less time which allows for shortened drug development times and increased throughput in testing labs.

 For example, when diagnosing hereditary diseases, identifying genetic fingerprints (used in forensic sciences and paternity testing), and detecting or diagnosing infectious diseases, Polymerase Chain Reaction (PCR) is often used to replicate the DNA being tested.  This is an exacting process, often times requiring the rapid heating and cooling of the DNA sample based on a predefined series of temperature steps. Simple temperature controllers can often overshoot set temperature points when ramping at these fast rates.  This can frequently lead to inaccurate test results.

 "The market is evolving toward faster chemistries used in DNA amplification. Too many manufacturers are using simple temperature controllers that are not sophisticated enough to manage fast thermal responses," explains Anders Kottenauer, Senior Vice President of Laird's Engineered Thermal Systems business. He adds, "Use of our new PCR Cycler technology can improve test accuracy and ultimately lead to the detection of new pathogens and treatment solutions.Ē

 The PCR Cycler Evaluation Kit, identified as model PC-24-TS-58, includes a programmable controller that utilizes an ultrafast thermal feedback loop and two control loops, one for the control side and one for the heat rejection side. These allow the controller to quickly and accurately adjust to the precise temperatures required throughout the process cycle without increasing test time or interfering with the results.

 The controller incorporates alarm features and a port for SD flash memory cards to log temperatures and electric current throughout the duration of DNA amplification.  This verifies that the device is operating effectively and that DNA has been driven to specified temperature set point ranges.

 The evaluation kit includes a thermoelectric assembly, cycling controller and graphical interface.

Benefits

  • Flexible temp control to accommodate sample and reagent types
  • Reduces stress on TEC and improves efficiency
  • Minimizes overshooting temperature set points
  • Superior temperature control stability
  • Monitors health of device and sample

For more information on the PCR Evaluation Kit Cooler visit http://www.lairdtech.com/products/pcr-cycler-evaluation-kit.

Editorís note

The vast majority of DNA replication methods using Polymerase Chain Reaction (PCR) use thermal cycling, alternately heating and cooling of the DNA sample based on a predefined series of temperature steps.

About Laird

Laird is a global technology company focused on providing systems, components and solutions that protect electronics from electromagnetic interference and heat, and that enable connectivity in mission critical systems through wireless applications and antenna systems.

Products are supplied to all sectors of the electronics industry including the Automotive, Mobile Device, Healthcare/ Medical, Computer/ Gaming, Telecommunications, Industrial/ Production, and Transportation markets.

Laird, a unit of Laird PLC, employs over 9,000 employees in more than 50 facilities located in 19 countries.

 

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